Tissue Typing

Donors and patients are matched by their HLA type, which is different from matching blood types. A simple cheek swab can help to determine whether you’re a close stem cell match for a patient. Read more at:

https://bethematch.org/transplant-basics/matching-patients-with-donors/how-donors-and-patients-are-matched/

Your baby’s DNA will be collected by a trained CELVI representative after birth, usually within 2 days. You will be contacted to arrange an appointment.

A cheek swab (buccal swab) is used to collect the sample for testing. This is a non-invasive way to collect DNA from the cells on the inside of the cheek.  The swab is rubbed along the inside the baby’s cheek to collect epithelial cells which contain DNA information needed for tissue typing.

Buccal swabs are generally preferred by those looking for DNA testing because they’re much less invasive than a blood test.

The Sunflower Fund registry will send the sample for tissue typing and register it on the Sunflower Fund Registry.

The results will be kept confidential in line with the World Marrow Donor Association guidelines and local regulations

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The treating doctor will determine the use of cord blood for treatment, depending on many factors, including the patient’s medical condition, the quality of the cord blood sample, if the patient’s own cord blood can be used or an adequately matched donor’s cord blood.The use of cord blood has been established in stem cell transplantation and has been used to treat more than 80 diseases. The use of cord blood in regenerative medicine is still being researched and there is no guarantee that treatments being studied in the laboratory, clinical trials, or other experimental treatments will be available in the future.The use of cord tissue stem cells is still in early research stages, and there is no guarantee that treatments using cord tissue stem cells will be available in the future. Cord tissue stem cells are found in the cord tissue which is stored whole. Additional processing will be required to isolate the stem cells from the tissue for use. CELVI (Pty) Ltd outsources all cord blood and tissue processing and storage activities to Next Biosciences in Midrand, South Africa, a licensed and AABB accredited facility.

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