Diseases Treated by Umbilical Cord Blood Transplantation Using Either Sibling or Unrelated Donors

Diseases Treated by Umbilical Cord Blood Transplantation Using Either Sibling or Unrelated Donors

Malignant Diseases

Malignant Diseases


  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myeloblastic Leukemia (AML)
  • Juvenile Chronic Myelogenous Leukemia (JMML)
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)


  • Non-Hodgkin Lymphoma (NHL)
  • Hodgkin Lymphoma (HL)

Lymphoproliferative disorders

  • Multiple myeloma

Myelodysplastic / myeloproliferative diseases

  • Myelodysplastic Syndrome
  • Myelofibrosis

Solid Tumours

  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma
  • Ewing sarcoma

Non-Malignant Diseases

Non-Malignant Diseases

Bone marrow failure syndromes

  • Fanconi Anemia
  • Idiopathic Aplastic Anemia
  • Blackfan-Diamond Syndrome
  • Dyskeratosis Congenita
  • Congenital dyserythropoietic anemia Hemoglobinopathies


  • Thalassemia
  • Sickle Cell Anemia
  • Paroxysmal nocturnal hemoglobinuria
  • Amegakaryocytic Thrombocytopenia Immune deficiencies

Immune deficiencies

  • Severe Combined Immunodeficiency
  • X-linked Lymphoproliferative Syndrome
  • Wiskott-Aldrich Syndrome
  • Kostman syndrome Metabolic disorders

Metabolic disorders

  • Krabbe’s Disease
  • Hurler Syndrome
  • Sanfilippo Syndrome
  • Hunter Syndrome
  • Gunther Disease
  • Osteopetrosis
  • Globoid Cell Leukodystrophy
  • Metachomatic Leukodystrophy
  • Adrenoleukodsytrophy
  • Tay-Sachs Disease
  • Lesch-Nyhan Syndrome
  • Sandhoff Disease
  • Other rare metabolic and primary immunodeficiency diseases

Diseases being studied

  • Type I and Type II Diabetes Mellitus
  • Thromboangitis Obliterans
  • Critical Limb Ischemia
  • Congenital Heart Disease
  • Idiopathic Dilated Cardiomyopathy
  • Skin—Wound/BurnLiver Cirrhosis
  • Epidermolysis BullosaViral Hepatitis
  • Rheumatoid Arthritis
  • Ulcerative Colitis / Inflammatory Bowel Disease
  • Systemic Lupus Erythematosus
  • Duchenne Muscular Dystrophy
  • Sweat Gland Diseases
  • Glaucoma
  • Corneal Epithelial Wounds
  • Diabetic Foot Ulcers
  • Spinal Cord Injury
  • Acute Ischemic Stroke
  • Neurodegenerative Disorders
  • Cerebral Palsy
  • Traumatic Brain Injury
  • Autism Spectrum Disorder
  • Hydrocephalus
  • Hypoxic-Ischemic Encephalopathy
  • In-Utero Brain Injury / Stroke
  • Amyotropic Lateral Sclerosis
  • Parkinson’s Disease
  • Childhood Hearing Loss
  • Infant Lung Disease
  • Preterm Neonatal Complications
  • Hypoplastic Left Heart Syndrome
  • Global Developmental Delay
  • Congenital Diaphragmatic Hernia

M-D-05.5.1 V1 – 2019/09/09

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The treating doctor will determine the use of cord blood for treatment, depending on many factors, including the patient’s medical condition, the quality of the cord blood sample, if the patient’s own cord blood can be used or an adequately matched donor’s cord blood.The use of cord blood has been established in stem cell transplantation and has been used to treat more than 80 diseases. The use of cord blood in regenerative medicine is still being researched and there is no guarantee that treatments being studied in the laboratory, clinical trials, or other experimental treatments will be available in the future.The use of cord tissue stem cells is still in early research stages, and there is no guarantee that treatments using cord tissue stem cells will be available in the future. Cord tissue stem cells are found in the cord tissue which is stored whole. Additional processing will be required to isolate the stem cells from the tissue for use. CELVI (Pty) Ltd outsources all cord blood and tissue processing and storage activities to Next Biosciences in Midrand, South Africa, a licensed and AABB accredited facility.

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