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What Cord Blood Treatments Exist?

Are there current uses for cord blood stem cells?

Yes.  More than 80 conditions or diseases have been treated using cord blood stem cells for more than 40 000 transplantations over the last 30 years.  Stem cell therapies are continuously evolving and improving, bringing new hope to patients and their families.

See a list of the more common diseases treated with cord blood stem cells below.  If you need more information, please click here.


  • Acute Leukemia
  • Chronic Leukemia
  • High-Risk Solid Tumors
  • Hodgkin & Non-Hodgkin Lymphoma
  • Myelodysplastic Syndromes

Blood Disorders

  • Aplastic Anemia
  • Beta Thalassemia
  • Diamond-Blackfan Anemia
  • Fanconi Anemia
  • Sickle Cell Disease

Immune Disorders

  • Chronic Granulomatous Disease
  • Hystiocytic Disorders
  • Leukocyte Adhesion Deficiency
  • Severe Combined Immunodeficiency Diseases (SCID)
  • Wiskott-Aldrich Syndrome

Metabolic Disorders

  • Krabbe Disease
  • Hurler Syndrome
  • Metachromatic Leukodystrophy
  • Sanfilippo Syndrome

Saving or donating cord blood stem cells makes them available to treat diseases like those listed above. For inherited genetic conditions, the child may not be able to use his or her own stem cells. In these cases, a matched sibling’s stem cells would be the first choice.

How is cord blood being used in medical treatments?

Cord blood has been used in established treatments as part of a stem cell transplant for more than 80 diseases, saving thousands of lives.

Umbilical cord stem cells have been used in regenerative medicine clinical trials to treat patients with cerebral palsy, autism, hearing loss, stroke and spinal cord injury.  Click here to read more.

What is the difference between a pre-clinical research study and a clinical trial?

Clinical trials are experimental treatments using human subjects. They are regulated by the South African Health Products Regulatory Authority (SAHPRA) (FDA or similar institutions in other countries) and conducted by physicians and medical institutions. Pre-clinical research involves the studies performed prior to clinical trials.

What is Regenerative Medicine?

Regenerative medicine boosts the repair response of diseased, dysfunctional or injured tissue.

The promising field of Regenerative Medicine is working to harness the power of the body to heal itself and to accelerate it in a clinically relevant way; to help the body heal better. The goal of this medicine is to find a way to cure previously untreatable injuries and diseases.

The U.S. Department of Health and Human Services has identified the value of this cutting-edge approach and stated that “regenerative medicine is a rapidly growing field of biomedicine that will revolutionize health care treatment.” In fact, it’s estimated that 1 in 3 people in the U.S. may benefit from a regenerative therapy in their lifetime21.

Four areas of development

  • Cellular Therapies
  • Medical devices and artificial organs
  • Tissue engineering and biomaterials
  • Clinical Translation

M-D-05.15 V1 – 2019/09/09

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The treating doctor will determine the use of cord blood for treatment, depending on many factors, including the patient’s medical condition, the quality of the cord blood sample, if the patient’s own cord blood can be used or an adequately matched donor’s cord blood.The use of cord blood has been established in stem cell transplantation and has been used to treat more than 80 diseases. The use of cord blood in regenerative medicine is still being researched and there is no guarantee that treatments being studied in the laboratory, clinical trials, or other experimental treatments will be available in the future.The use of cord tissue stem cells is still in early research stages, and there is no guarantee that treatments using cord tissue stem cells will be available in the future. Cord tissue stem cells are found in the cord tissue which is stored whole. Additional processing will be required to isolate the stem cells from the tissue for use. CELVI (Pty) Ltd outsources all cord blood and tissue processing and storage activities to Next Biosciences in Midrand, South Africa, a licensed and AABB accredited facility.

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